Availability

  • Request Lead Time
  • In stock and ready for quick dispatch
  • Usually dispatched within 5-10 working days

Cytochrome C Polyclonal Antibody

Catalog Number: GRP178

Product Overview
Product Name Cytochrome C Polyclonal Antibody
Catalog Number GRP178
Species/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications FC, ICC, IF, IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from human Cytochrome C (public_immunogen_range: 50-89/105)
Alternative Names
Product Properties
Form/Appearance Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration 1ug/ul
Storage Store at -20°C for 12 months.
Note For research use only.
Isotype IgG
Clonality Polyclonal
Purity Purified by Protein A.
Uniprot ID P99999
Entrez 54205
Product Description

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Application Notes
Dilution Range WB: 1:300-1000, FC: 1:20-100, IHC-P: 1:200-400, IF: 1:50-200
Reviews
Write Your Own Review
You're reviewing:Cytochrome C Polyclonal Antibody - GRP178
Your Rating