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Glutamine synthetase antibody [GT1055]

Catalog Number: GRP173

Product Overview
Product Name Glutamine synthetase antibody [GT1055]
Catalog Number GRP173
Species/Host Mouse
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications ICC, IF, IHC-Fr, IHC-P, WB
Immunogen Full length human Glutamine synthetase Recombinant protein.
Alternative Names
Product Properties
Form/Appearance Liquid: PBS
Concentration 1 mg/ml
Storage Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Note For research use only.
Isotype IgG1
Clonality Monoclonal
Purity Affinity purified by Protein G.
Clone ID GT1055
Uniprot ID P15104
Entrez 2752
Product Description

Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling (Haberle et al., 2005 [PubMed 16267323]). Fetal glutamine requirements are very high and depend largely on active glutamine synthesis and the release of glutamine into the fetal circulation by the placenta. Glutamine synthetase (EC 6.3.1.2), also called glutamate-ammonia ligase (GLUL), is expressed throughout the body and plays an important role in controlling body pH and in removing ammonia from the circulation. The enzyme clears L-glutamate, the major neurotransmitter in the central nervous system, from neuronal synapses (see references in Clancy et al., 1996 [PubMed 8975719]).[supplied by OMIM]

Application Notes
Dilution Range WB: 1:500-1:3000,ICC: 1:100-1:1000,IHC-P: 1:100-1:1000,IHC-Fr: 1:100-1:1000
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