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TDP43 antibody [GT225]

Catalog Number: GRP172

Product Overview
Product Name TDP43 antibody [GT225]
Catalog Number GRP172
Species/Host Mouse
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Tested applications ICC, IF, IHC-P, WB
Immunogen Recombinant protein encompassing a sequence within the center region of human TDP43. The exact sequence is proprietary.
Alternative Names
Product Properties
Form/Appearance Liquid: PBS
Concentration 1 mg/ml
Storage Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Note For research use only.
Isotype IgG2b
Clonality Monoclonal
Purity Affinity purified by Protein G.
Clone ID GT225
Uniprot ID Q13148
Entrez 23435
Product Description

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]

Application Notes
Dilution Range WB: 1:500-1:3000,ICC: 1:100-1:1000,IHC-P: 1:100-1:1000
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